Ophelia from Hamlet: I've always wondered if she was really the lost cause everyone thought. Unrequited love and teenage hormones are a rough combo, but a little understanding may have prevented her tragic fate.
Kahlan from Wizard's First Rule: Strong, smart, and determined, and wise, she's always been one of my favorite heroines. She's got all the right answers, and if not then she's got a plan to get them.
Mystique from X-Men (anything): For way too many reasons to list, she's just fucking awesome.